FRAX Equation (UK Version):
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The FRAX® tool is a computer-based algorithm that calculates the 10-year probability of a major osteoporotic fracture (hip, clinical spine, humerus or wrist fracture) and the 10-year probability of hip fracture. The UK version is specifically calibrated for the UK population.
The calculator uses the FRAX equation:
Where all risk factors are weighted according to their contribution to fracture risk.
Details: FRAX score helps clinicians identify patients who would benefit from osteoporosis treatment, particularly those with intermediate risk where clinical judgment is needed.
Tips: Enter all required information. BMD is optional but improves accuracy. Age range is limited to 40-90 years as per FRAX guidelines.
Q1: Why use the UK version of FRAX?
A: The UK version is calibrated to UK fracture and mortality rates, providing more accurate estimates for this population.
Q2: What are the treatment thresholds in the UK?
A: In the UK, treatment is generally recommended when the 10-year probability of major osteoporotic fracture is ≥20% or hip fracture ≥3%.
Q3: How important is BMD measurement?
A: While FRAX can be used without BMD, including BMD (especially femoral neck) significantly improves prediction accuracy.
Q4: Can FRAX be used for younger patients?
A: The algorithm is validated only for ages 40-90. For younger patients, clinical judgment is required.
Q5: How often should FRAX be recalculated?
A: Reassessment every 2-5 years is reasonable, or when new risk factors emerge.