1. What is the eGFR to CrCl Conversion?

The Kidney Foundation adjustment converts eGFR (normalized to 1.73m² body surface area) to actual creatinine clearance (CrCl) by accounting for the patient's actual body surface area.

2. How Does the Calculator Work?

The calculator uses the adjustment formula:

Where:

• \( eGFR \) — Estimated glomerular filtration rate
• \( BSA \) — Patient's body surface area in m²
• 1.73 — Standard BSA used for eGFR normalization

Explanation: This adjustment accounts for differences in body size when converting from standardized eGFR to actual creatinine clearance.

3. Importance of CrCl Calculation

Details: Actual CrCl is often needed for precise medication dosing, while eGFR is standardized for kidney function assessment.

4. Using the Calculator

Tips: Enter eGFR in mL/min/1.73m² and actual body surface area in m². All values must be valid (eGFR > 0, BSA > 0).

5. Frequently Asked Questions (FAQ)

Q1: Why convert eGFR to CrCl?
A: eGFR is standardized for kidney function assessment, while CrCl reflects actual clearance which may be needed for drug dosing.

Q2: How do I get my BSA?
A: BSA can be calculated using formulas like DuBois or Mosteller, or measured clinically.

Q3: When is this conversion most important?
A: Particularly important for patients with very large or small body size when precise drug dosing is required.

Q4: Are there limitations to this conversion?
A: This assumes similar creatinine generation and tubular secretion between individuals of different sizes.

Q5: Should I use this for all medications?
A: Check specific drug prescribing information - some use eGFR directly while others require CrCl.