Sample Size Formulas:
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Sample size calculation determines the number of participants needed in a study to detect an effect of a given size with a certain degree of confidence. It helps ensure studies are adequately powered without wasting resources.
The calculator uses two standard formulas:
Where:
Explanation: The formulas account for the variability in data and desired precision to determine how many samples are needed.
Details: Proper sample size ensures study validity, prevents underpowered studies, and optimizes resource use. Too small samples may miss effects, while too large wastes resources.
Tips: Select calculation type (means or proportions), enter Z-score (1.96 for 95% CI), standard deviation or proportion, and desired margin of error. All values must be positive.
Q1: What Z-score should I use?
A: Common values are 1.96 (95% CI) or 2.576 (99% CI). The exact value depends on your desired confidence level.
Q2: How to estimate standard deviation?
A: Use pilot data, previous studies, or literature. For proportions, 0.5 gives the most conservative estimate.
Q3: What's a reasonable margin of error?
A: Typically 5% (0.05) for proportions. For means, it depends on the measurement scale and expected variability.
Q4: Does this work for small populations?
A: For populations <10,000, use finite population correction: \( n_{adj} = \frac{n}{1 + \frac{n-1}{N}} \) where N is population size.
Q5: What about different study designs?
A: More complex designs (e.g., cluster RCTs) require additional adjustments to the sample size calculation.