FRAX Equation:
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The FRAX® tool is a computer-based algorithm that calculates the 10-year probability of a major osteoporotic fracture (hip, clinical spine, humerus or wrist fracture) and the 10-year probability of hip fracture. The UK version is calibrated to the epidemiology of fracture and death in the UK.
The calculator uses the FRAX equation:
Where all risk factors contribute to the final probability score.
Details: The FRAX score helps clinicians identify patients who would benefit from osteoporosis treatment, particularly those with clinical risk factors but without a bone mineral density measurement.
Tips: Enter all required information accurately. BMD is optional but increases accuracy when available. The calculator is valid for patients aged 40-90 years.
Q1: What is considered a high FRAX score?
A: In the UK, intervention thresholds are typically set at ≥20% for major osteoporotic fracture or ≥3% for hip fracture.
Q2: How accurate is FRAX without BMD?
A: FRAX is reasonably accurate without BMD, but including BMD measurements improves precision, particularly in intermediate-risk patients.
Q3: Can FRAX be used for younger patients?
A: The calculator is validated only for ages 40-90. For younger patients, clinical judgment is required.
Q4: How often should FRAX be recalculated?
A: Reassessment every 2-5 years is reasonable, or when new risk factors emerge.
Q5: Does FRAX account for falls risk?
A: No, FRAX doesn't incorporate falls risk. This should be considered separately in clinical decision-making.