FraX Score Calculation

FRAX Equation:

\[ \text{FRAX (\%)} = f(\text{Age}, \text{Sex}, \text{Weight}, \text{Height}, \text{Previous Fracture}, \text{Parent Fractured Hip}, \text{Current Smoking}, \text{Glucocorticoids}, \text{Rheumatoid Arthritis}, \text{Secondary Osteoporosis}, \text{Alcohol}, \text{BMD}) \]

Age:

years

Sex:

Weight:

Height:

Previous Fracture:

Parent Fractured Hip:

Current Smoking:

Glucocorticoids:

Rheumatoid Arthritis:

Secondary Osteoporosis:

Alcohol 3+ units/day:

Femoral Neck BMD:

g/cm² (optional)

FRAX Score:

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1. What is the FRAX Score?

The FRAX® tool is a computer-based algorithm that calculates the 10-year probability of a major osteoporotic fracture (hip, clinical spine, humerus or wrist fracture) and the 10-year probability of hip fracture. It was developed by the World Health Organization Collaborating Centre for Metabolic Bone Diseases.

2. How Does the Calculator Work?

The calculator uses the FRAX equation:

Where:

Age — Between 40 and 90 years
Sex — Male or Female
Weight — Body weight in kg
Height — Body height in cm
Previous Fracture — Previous fragility fracture (yes/no)
Parent Fractured Hip — Parental history of hip fracture (yes/no)
Current Smoking — Current smoker (yes/no)
Glucocorticoids — Current or past use of oral glucocorticoids (yes/no)
Rheumatoid Arthritis — Rheumatoid arthritis (yes/no)
Secondary Osteoporosis — Conditions associated with osteoporosis (yes/no)
Alcohol — Alcohol intake of 3 or more units/day (yes/no)
BMD — Femoral neck BMD (optional)

3. Importance of FRAX Calculation

Details: The FRAX score helps clinicians identify patients at high risk of osteoporotic fractures who may benefit from treatment. It provides an evidence-based approach to fracture risk assessment.

4. Using the Calculator

Tips: Enter all required information accurately. BMD is optional but provides more accurate results when available. The calculator is valid for ages 40-90.

5. Frequently Asked Questions (FAQ)

Q1: What is considered a high FRAX score?
A: Generally, a 10-year major osteoporotic fracture probability ≥20% or hip fracture probability ≥3% is considered high risk.

Q2: Can FRAX be used without BMD?
A: Yes, FRAX can be calculated without BMD, but including BMD makes the assessment more accurate.

Q3: How often should FRAX be recalculated?
A: Reassessment is recommended every 2-5 years or when clinical risk factors change significantly.

Q4: Are there limitations to FRAX?
A: FRAX doesn't account for dose of glucocorticoids, number of prior fractures, or risk of falls. It's less accurate for certain ethnic groups.

Q5: Can FRAX be used for treatment monitoring?
A: No, FRAX is for initial risk assessment, not for monitoring treatment response.